![]() It was good in terms of cold and ice retention, and there was still some solid ice in the cooler 24 hours later. We appreciated how waterproof the cooler is, too. We also like some extra touches on the Boss compared to other coolers we tested, such as the additional pockets and places to attach gear you don't want inside the actual cooler. ![]() IceMule has emphasized the weight distribution of this backpack by including dual-zone suspension. They also liked the chest and waist straps. Our testers loved that the straps are not too thin and not too bulky, and the efficiency of the cooler's back padding and ventilation. "This is the best big cooler for carrying," one tester noted. And while the pack is good for cold and ice-retention (more on that in a bit), our testers particularly enjoyed how easy it was to carry despite its bulk. The IceMule Boss is heavy-duty, rugged, and spendy. Size: 13 x 7 x 17.5 inches | Capacity: 42 cans (claimed) | Weight: 2.18 poundsĭifficult to see items in main compartment And with the proper two-thirds ice ratio, we only fit 14 cans. Our one nitpick is we couldn't fit the 42 cans Igloo claims (it was more like 40). Our testers found this pack comfortable to carry thanks to adjustable shoulder straps and a sternum strap for stability. We also love that this cooler has a few more features, including an integrated bottle opener, external pockets, and oversized webbed loops for attaching extra gear. ![]() The zippered entry features a wide opening, which our testers found efficient for packing and unpacking larger items. The insulated liner inside the cooler is also odor- and stain-resistant and easy to wipe clean ideal for a backpack cooler, which tends to get slung around and inverted more than a traditional hardside cooler. Igloo's Snapdown does just that with its advanced MaxCold insulation. Coolers are first meant to insulate and keep your items chilled. Simply put: We have yet to see a more cost-efficient backpack cooler than the Outdoor Pro Snapdown. Other coolers performed as well as the Igloo during our tests but also cost $100-plus more. We picked Igloo's Outdoor Pro Snapdown Backpack Cooler as our overall winner for its functionality and value.
0 Comments
PTS-Formic Acid–A strong corrosive material that is used in tanning formulas. Water must be 80 degrees for proper degreasing. ![]() Bears and most fur bearing animals must be degreased or the fur will be difficult to dry and fluff. PTS-Degreaser–Degreasing of certain skins is a requirement for good results. You want the skin to act like a sponge and suck the oil into the leather. After removing the cape from the alum bath, drain the skin and allow the flesh side to dry to a thirsty condition. The key to a properly oiled cape is the timing after the tanning bath and the oiling of the cape. Oil should be used at or slightly above room temperature. PTS-Tanning Oil-This is a professional quality tanning oil to be used on any cape or skin to be mounted. PROFESSIONAL QUALITY PRODUCTS-LOWER COST-MORE PROFIT Also individual results are determined by the individuals ability to shave or thin the skin, which is essential for good stretch in the finished product. We recommend that skins to be rugged, should be sent to a professional tanner due to the equipment necessary to properly finish dry tanned skins. The following steps should be followed for the tanning of capes and skins to be mounted. I have compiled step by step instructions for the use of these products. By purchasing these materials directly, we have been able to significantly reduce the cost to the taxidermist who wants to tan his own skins. With this system you will have the same quality as your present tan, but at a reduced cost of materials. With this in mind, we decided to look into the possibility of offering a line of the same products and procedures that professional tanners use. If you are following the basic tanning procedure of formic acid, salt and alum tan, then simply use professional tanning oils that are much cheaper than the products now being sold. The fact is that you are buying tanning oils and other products at a very inflated price. The directions for use of these products have changed and currently recommend the same steps as the basic tanning procedure that professional tanners have used for years. The bottom line is that these products did not work as stated and a multitude of problems developed. Instructions were to skin, salt and paint on these miracle tanning creams, let dry, re-soak and mount in the future. Initially these products were claimed to be a miracle short cut to the tanning process. ![]() Over the past several years there have been several tanning products introduced to the taxidermy market. ![]() You may have some issues syncing sound and picture, but a good projector will have a setting to compensate for this. With that, you can hook up a pair of headphones or even a Bluetooth speaker. If you want to go one better, some include a headphone socket or – better still – Bluetooth connectivity. The quality varies enormously, with some dishing out a timid, tinny racket and others producing a half-decent impression of stereo sound. If you’re using a portable projector, you probably don’t want to lug a full surround-sound setup with you, so most include built-in speakers. The same goes for auto-focus features, although most models have a manual slider or wheel. The best portable projectors do it automatically, so you can spend less time setting up your screen and projector and more time enjoying what you want to watch. Nearly all projectors have some form of correction to sort this out. This distorts the picture so that the rectangular image looks like a trapezoid (or worse) – an effect known as keystoning. Projectors are best positioned with the lens facing directly at the centre of the screen, but in practice this isn’t usually practical, so the projector has to be placed above or below – or even to one side – and angled up, down, left or right. Keystone correction is another must-have. Try to fill a 120in screen with a 100 ANSI lumens projector and you won’t get much contrast, colour or anything else. Remember that your maximum size will also be affected by the brightness. ![]() Most of these portable models have a relatively short throw, and the shorter the better if you’re stuck for space or planning to project from a coffee table. All projectors have what’s called a “throw ratio”, which determines how big the picture will be at any given distance, and some are what’s called short-throw projectors, meaning they’re designed to give a bigger picture even from a distance of one or two metres. Because of the way they work, by beaming an image onto a flat surface, the size of the projected picture will be determined by the distance between the projector and screen. As a rule of thumb, the more you spend, the brighter the image and the higher the resolution, giving you a better experience overall. In a dark room, you can still get a decent picture, but if you’re expecting true cinema quality or something that will work with the curtains wide open, you may end up feeling disappointed. LED portable projectors tend to achieve anything from 100 to 2,000 ANSI lumens, with the vast majority sitting somewhere between 300 and 800 ANSI lumens. Even in a sunlit room, the picture should still be watchable. A proper home cinema projector will dish out 2,000 ANSI lumens or more of brightness, so that you can have bright whites, deep blacks and rich colours in dark conditions. ![]() You won’t get the same levels of contrast and brightness with a portable projector, either. Sounds good? You might just have found a new way to enjoy your favourite TV, games and films. Better yet, because they’re small, light and relatively cheap, you won’t mind lugging them around. Given decent weather, you can even use them outdoors in the summer. You can use them with a big screen in the living room or pair them with a portable screen when you take them away on holiday. With battery-powered operation, built-in speakers and lamps that last for tens of thousands of hours, these portable projectors are perfect for take-anywhere entertainment. You can now buy a projector the size of a Rubik’s cube or smartphone. But a few years ago the combination of small, high-quality DLP chips and energy-efficient LED lamps made it possible to build projectors the size of a hardback book or even smaller. They used to be massive things, ran hot, were power-hungry and needed a chunky stand or coffee table to sit on – if not a dedicated home cinema room. In case you haven’t noticed, projectors have got a lot smaller. ![]() For more information, read our affiliate disclosure. If you click an affiliate link and subsequently make a purchase, we will earn a small commission at no additional cost to you (you pay nothing extra). Important disclosure: we're proud affiliates of some tools mentioned in this guide. We will explore the best animation software apps for each type of animation in each category. To make it easier for you to navigate through this article and select the powerful animation tools based on the type of animation you are interested in, we have separated them into four categories. We will take a look at their prices, functionalities, and difficulty levels, as well as their pros and cons.īut before we start, we should mention that there are four different types of animation: In this guide, we will explore the top 25 animation software apps in 2023. Īdditionally, looking at the sheer volume of products out there, you might be scratching your head and thinking to yourself, ‘ Where do I even begin?’.ĭon’t fret! You are one step closer to making your final decision. ![]() The selection process can be tricky when exploring and choosing the best animation software app. In addition, a plethora of different animation software apps cater to every type of animation you need to create. Fast forward to 2023, and anyone, whether they are a professional animation maker or not, can use computer-generated imagery (CGI) to create any type of animation. Even though people started experimenting with computer graphics as early as the 1940s, it was during the early 1960s that computer graphics rocketed.ĭuring that time, digital computers had already become widely established and became mainstream in the 1970s, after the mass production of the microprocessor in 1971. The history of computer animation began a few decades later. Animation is widely used in the education sector as well as for research purposes to create realistic scientific visualizations. Various other industries, such as Advertisement, Marketing, Gaming, Retail, Architecture, and Engineering, use animation in multiple ways. Nowadays, animation is not only used in the entertainment industry. Since the creation of the world’s first animated film in 1908 by French cartoonist and animator Émile Cohl, the world of animation has come a long way. ![]() Groups: -groupīTW The previous command was constructed based on a search of tools package names: pkgutil -pkgs | grep -i tools If Xcode is installed, you would get a version code that should match up with the Build Number on Apple’s web page: Xcode 14.3.1įor a more precise version number and other info (macOS Mavericks version and up): pkgutil -pkg-info=_ExecutablesĪ sample response, at time of writing: package-id: _Executables Xcode-select: error: tool ‘Xcodebuild’ requires Xcode, but active developer directory ‘/Library/Developer/CommandLineTools’ is a command line tools instance If Command Line Tools was installed, you would see: Press q to exit from the multi-page viewer.įrom within a Terminal, type: /usr/bin/Xcodebuild -version See it’s a binary executable if you view the file: cat /usr/bin/gcc On an Intel Mac, the response is a path to the file at: /usr/bin/gcc See the link’s location using a Linux utility: which gcc Would yield (at time of writing): 16143 directories, 72910 files If you have the tree utility installed: tree /Library/Developer/CommandLineTools | tail -1 How many folders and files were installed? The response would have more than what’s in CommandLineTools: Applications Library Makefiles Platforms Toolchains Tools usr If Xcode.app was installed: ls -al /Applications/Xcode.app/Contents/Developer/ If CommandLineTools was installed: ls -al /Library/Developer/CommandLineTools ![]() If Xcode.app was installed, you would see (at time of writing): Apple clang version 14.0.3 (clang-1403.0.22.14.1) InstalledDir: /Applications/Xcode.app/Contents/Developer/Toolchains/XcodeDefault.xctoolchain/usr/bin ![]() Previously, it was instead: Configured with: -prefix=/Library/Developer/CommandLineTools/usr -with-gxx-include-dir=/Library/Developer/CommandLineTools/SDKs/MacOSX.sdk/usr/include/c++/4.2.1Īpple clang version 13.0.0 (clang-1300.0.29.3)Ĭonfigured with: -prefix=/Library/Developer/CommandLineTools/usr -with-gxx-include-dir=/Library/Developer/CommandLineTools/SDKs/MacOSX.sdk/usr/include/c++/4.2.1Īpple clang version 11.0.3 (clang-1103.0.32.62)Īpple LLVM version 10.0.1 (clang-1001.0.46.4) InstalledDir: /Library/Developer/CommandLineTools/usr/bin If the program is using CommandLineTools, you would see (at time of this writing): Apple clang version 15.0.0 (clang-1500.0.28.1.1) If the response is “command not found”, it’s not installed. Verify the version of GCC installed: gcc -version Use `sudo Xcode-select -switch path/to/Xcode.app` to specify the Xcode that you wish to use for command line developer tools, or use `Xcode-select -install` to install the standalone command line developer tools.Īgain, if “Command not found” appears, either install CommandLineTools or install XCode.app, then return here. If neither is installed: xcrun: error: active developer path ("/Library/Developer/CommandLineTools") does not exist ![]() Applications/Xcode.app/Contents/Developer/usr/bin/gcc If Xcode.app is installed, the response would be: Library/Developer/CommandLineTools/usr/bin/gcc If Command Line Utilities is installed, the response would be: To identify the path to one of the utilities (gcc), use the xcrun utility that comes with macOS: xcrun -find gcc If the Xcode-select command is not found, choose to either install Command Line Tools or install the full Xcode IDE.Applications/Xcode.app/Contents/Developer If XCode.app was installed, you should instead see:.If XCode CLI was installed, you should see:.In a Terminal window, find out what has been installed: xcode-select -p Use Apple’s xcode-select command to identify where to find gcc and other Apple Developer utilities: Developers using Mac Books but NOT developing apps to run on an Apple platform can install just the CommandLineTools. Library/Developer/CommandLineTools => if installed using CommandLineToolsĬhoose one. $HOME/Applications/Xcode.app => if installed using Apple’s Xcode IDE Utilities needed can be obtained from two different folders, installed two different ways: “PROTIP:” here highlight information I haven’t seen elsewhere on the internetīecause it is hard-won, little-know but significant factsīased on my personal research and experience. Not intended to represent any employer (past or present). NOTE: Content here are my personal opinions, and This tutorial describes how to install several utilities needed by developers running HomeBrew, Python, and other programs on Macs: Install XCode from Apple’s web App Store. ![]() This results in greater scalability while ensuring a high definition user experience. For example, corporate communications videos, training videos, or when a third party hosts the content.įor more information about HTML5 Video Redirection, see HTML5 multimedia redirection.įlash Redirection offloads the processing of most Adobe Flash content (including animations, videos, and applications) to users’ LAN- and WAN-connected Windows and 32-bit Linux x86 devices, which reduces server and network load. HTML5 Video Redirection is ideal to control the multimedia content. We haven’t decided in which versions of XenApp and XenDesktop to exclude the Flash Redirection code, but we recommend that you switch to HTML5 Video Redirection whenever possible. When that happens, users can no longer enable or run Flash in Internet Explorer.Ĭitrix aligns with Microsoft policy and continues to maintain and support HDX Flash Redirection until the end of 2020. They are removing Flash from Windows by the end of 2020. Microsoft announced that they are phasing out Flash support in Internet Explorer before the Adobe date. ![]() Adobe plans to stop updating and distributing the Flash Player at the end of 2020. On July 25, 2017, Adobe announced End of Life (EOL) for Flash. Questo articolo è stato tradotto automaticamente. (Aviso legal)Įste artigo foi traduzido automaticamente. (Clause de non responsabilité)Įste artículo ha sido traducido automáticamente. (Haftungsausschluss)Ĭe article a été traduit automatiquement. This article has been machine translated.ĭieser Artikel wurde maschinell übersetzt. Questo contenuto è stato tradotto dinamicamente con traduzione automatica. (Aviso legal)Įste texto foi traduzido automaticamente. (Clause de non responsabilité)Įste artículo lo ha traducido una máquina de forma dinámica. (Haftungsausschluss)Ĭet article a été traduit automatiquement de manière dynamique. This content has been machine translated dynamically.ĭieser Inhalt ist eine maschinelle Übersetzung, die dynamisch erstellt wurde. Install Session Recording with database high availabilityĬonfigure permissions for VDAs earlier than XenDesktop 7 Install, upgrade, and uninstall Session RecordingĮnable or disable live session playback and playback protection Pass-through authentication and single sign-on with smart cardsįederated Authentication Service architectures overviewįederated Authentication System how-to - configuration and managementīest practices, security considerations, and default operationsĬompare, prioritize, model, and troubleshoot policiesĬonfigure COM Port and LPT Port Redirection settings using the registryĬonnector for Configuration Manager 2012 policy settings Integrate XenApp and XenDesktop with NetScaler Gateway Security considerations and best practices Microsoft Azure virtualization environments Microsoft System Center Configuration Manager environments Microsoft System Center Virtual Machine Manager virtualization environments Microsoft Azure Resource Manager virtualization environments Section 508 Voluntary Product Accessibility Template ![]() Interested in getting the latest crime bulletin updates? Join the Campus Safety Listserv. The tractor trailer has a Chiquita logo on the side. For more information, click on the Campus Safety link in Related Information. A witness told CHP the semi appeared to have lost control and jack-knifed. ![]() UCLA Transportation coordinates efforts with the UCLA Police to provide information, programs and services focused on safety. Tune your radio to AM 1630 when on campus or in Westwood. UCLA has an on-campus radio station which operates around the clock, seven days a week, broadcasting local emergency and travel advisories to UCLA employees, students and visitors. also gives you the option to sign up for a service delivering more personalized reports on your route, including travel times, via the Web, email or phone, for a modest monthly fee.
![]() ^ Donnelly ML, Luke G, Mehrotra A, Li X, Hughes LE, Gani D, Ryan MD (May 2001).^ "Cleavage Activity of Aphtho- and Cardiovirus 2A Oligopeptidic Sequences"."2A self-cleaving peptide-based multi-gene expression system in the silkworm Bombyx mori". ^ Wang Y, Wang F, Wang R, Zhao P, Xia Q (November 2015)."Design and construction of 2A peptide-linked multicistronic vectors". ^ a b Szymczak-Workman AL, Vignali KM, Vignali DA (February 2012)."Cleavage of foot-and-mouth disease virus polyprotein is mediated by residues located within a 19 amino acid sequence". ^ Ryan MD, King AM, Thomas GP (November 1991)."Structures and Corresponding Functions of Five Types of Picornaviral 2A Proteins". ^ Yang X, Cheng A, Wang M, Jia R, Sun K, Pan K, et al."Occurrence, function and evolutionary origins of '2A-like' sequences in virus genomes". ^ Luke GA, de Felipe P, Lukashev A, Kallioinen SE, Bruno EA, Ryan MD (April 2008).Live Imaging In Zebrafish: Insights Into Development And Disease. ^ Sampath Karuna Roy Sudipto (30 August 2010)."Systematic comparison of 2A peptides for cloning multi-genes in a polycistronic vector". ^ a b c d Liu Z, Chen O, Wall JB, Zheng M, Zhou Y, Wang L, et al.However, the level of drop-off detected in this study varied widely depending on the exact construct used, with some constructs showing little evidence of drop-off furthermore, within a tri-cistronic transcript it reported a higher level of ribosome drop-off after one 2A sequence than after two 2As combined, which is at odds with a linear model of translation. One study reported that 2A sites cause the ribosome to fall off approximately 60% of the time, and that, together with ribosome read-through of about 10% for P2A and T2A, this results in reducing expression of the downstream peptide chain by about 70%. Therefore, up to 50% of F2A-linked proteins can remain in the cell as a fusion protein, which might cause some unpredictable outcomes, including a gain of function. Incomplete cleavage ĭifferent 2A peptides have different efficiencies of self-cleaving, T2A and P2A being the most and F2A the least efficient. ĢA peptides, when combined (or not) with the IRES elements, can make it possible to generate multiple separated peptides within a single transcript. Inserting the CDS of a 2A peptide into the fusing point or replacing the linker sequence with the CDS of a 2A peptide protein can cleave the fused protein into two separated peptides, rescuing the function of the two peptides. The 2A peptides can be applied when the fused protein doesn’t work. In genetic engineering, the 2A peptides are used to cleave a longer peptide into two shorter peptides. However, it is believed to involve ribosomal "skipping" of glycyl-prolyl peptide bond formation rather than true proteolytic cleavage. The exact molecular mechanism of 2A-peptide-mediated cleavage is still unknown. The apparent cleavage is triggered by ribosomal skipping of the peptide bond between the proline (P) and glycine (G) in C-terminal of 2A peptide, resulting in the peptide located upstream of the 2A peptide to have extra amino acids on its C-terminal end while the peptide located downstream the 2A peptide will have an extra proline on its N-terminal end. Adding the optional linker “ G S G” (Gly-Ser-Gly) on the N-terminal of a 2A peptide helps with efficiency. The following table shows the sequences of four members of 2A peptides. F2A is derived from foot-and-mouth disease virus 18 E2A is derived from equine rhinitis A virus P2A is derived from porcine teschovirus-1 2A T2A is derived from thosea asigna virus 2A. Members įour members of 2A peptides family are frequently used in life science research. The name "2A" itself comes from the gene numbering scheme of this virus. For example, F2A, the first described 2A peptide, is derived from foot-and-mouth disease virus. The members of 2A peptides are named after the virus in which they have been first described. 2A peptides are used to help generate polyproteins by causing the ribosome to fail at making a peptide bond. These peptides share a core sequence motif of D圎xNPGP, and are found in a wide range of viral families. Class of peptides An illustration of 2A peptide function: when the CDS of a 2A peptide is inserted between two CDSs of protein, the peptide will be translated into two proteins folding independently due to ribosome skipping (not due to cleavage as shown in the figure).ĢA self-cleaving peptides, or 2A peptides, is a class of 18–22 aa-long peptides, which can induce ribosomal skipping during translation of a protein in a cell. Its court system has undergone a drastic shift due to a mass persecution of lawyers under the Defense Culpability Act. Located at the western edge of the Far East, Khura'in is a kingdom of spirit mediums, with a religion centered around its founder, the Holy Mother. The opening animated scene in-game can appear to conflict with the events shown in this animated prologue, but Yamazaki has explained that the in-game scene was made to be understandable to people who had not seen the prologue, leaving only vague hints of the prologue's events. An English dubbed version of the video was shown at Anime Expo in early July 2016 before being uploaded to official YouTube channels on August 25. In March 2016, as part of a Twitter campaign, an 8-minute anime video was released appearing to depict events shortly prior to those in the game. To make matters worse, Justice must also face a figure from his past at the prosecutor's bench. Meanwhile, in Los Angeles, Apollo Justice and Athena Cykes remain to look after the Wright Anything Agency, only to face a crisis that not only affects one of its members, but the fate of the entire Agency. However, the country is on the tipping point of revolution instigated by the rebel Dhurke Sahdmadhi and his Defiant Dragons group. In the Far Eastern kingdom of Khura'in, Phoenix Wright and Maya Fey come into conflict with a court system that has done away with attorneys and instead views the victim's final moments via the Divination Séance to determine guilt. Unlike previous main series games, Phoenix Wright: Ace Attorney - Spirit of Justice takes place in two different settings. The iOS version includes only The Foreign Turnabout, with the remaining five episodes and the costume set all released as paid DLC, while the Android version includes all of the aforementioned content in the initial cost. iOS and Android versions were released on September 21st worldwide. The game was released on 9th June 2016 in Japan for Nintendo 3DS, and worldwide digitally only on September 8th, with the Special Episode and costume set released as paid DLC. Yoriki Daigo was the lead planner, and Naotaka Noda was the main programmer. ![]() ![]() Masakazu Eguchi was also a writer for the game. It was produced by Motohide Eshiro, with Takeshi Yamazaki and Takuro Fuse as co-directors. " Turnabout Trial 6") is the sixth installment of the Gyakuten Saiban series, and the tenth installment overall in the Ace Attorney series of text adventure video games. Phoenix Wright: Ace Attorney - Spirit of Justice (逆転裁判 6, Gyakuten Saiban 6 lit. PEGI: 12 / 16 * (Originally 16 before and just after release, later changed to 12 for unknown reason)ĪCB: PG / M * (Originally rated M via the automated classification process when released for the 3DS, later changed to PG for the Android / IOS release) These tests most often use techniques called RT-PCR (reverse-transcription polymerase chain reaction) or isothermal amplification. They were the first type of COVID test to be authorized and widely used. Molecular tests detect the presence of viral genetic material in a sample. Molecular tests are the most accurate type of COVID tests, rapid or not. The FDA has also authorized a rapid COVID breath test, but it’s not widely available yet. ![]() These tests work differently in how they detect SARS-CoV-2, the virus that causes COVID. There are two different types of rapid COVID tests available: And you can get results with these tests from the comfort of your home. You can also buy these tests without an order or prescription from a provider. What’s more, many rapid tests are available over the counter (OTC). They don’t need an outside laboratory to process. You can do rapid tests at point-of-care, like a testing site or a provider’s office. In general, most rapid tests provide results in 15 to 30 minutes. The fastest test currently available - ID NOW by Abbott - can detect the virus in 13 minutes or less. Compared to standard tests, rapid tests are often simpler. The key difference between rapid tests and standard laboratory tests is how long they take to process results.Īs the name suggests, rapid tests can produce fast results. Here we’ll cover the basics of rapid COVID tests, how fast they are, and the accuracy of the results. Rapid COVID tests are available at healthcare offices and the shelves of your local pharmacy or supermarket. ![]() But with fewer roadblocks and improvements in rapid testing, now you can get faster results. ![]() Early on, it sometimes took days to weeks to get test results. Since the start of the COVID-19 pandemic, over 1 billion COVID tests have been performed in the U.S. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |